TKA: preoperative methylprednisolone effective for pain and recovery .
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Effect of high-dose preoperative methylprednisolone on pain and recovery after total knee arthroplasty: a randomized, placebo-controlled trial
Br J Anaesth. 2011 Feb;106(2)48 total knee arthroplasty (TKA) patients were preoperatively administered either a single high-dose of methylprednisolone (MP) or a placebo to evaluate the efficacy of MP as an analgesic and its effect on early recovery. Patients were primarily assessed for pain through different measures during walking and at rest, along with several other secondary outcomes. The study demonstrated that methylprednisolone may be an effective analgesic and could contribute to improved immediate recovery in TKA patients.
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