TKA: Interval clamping drain provides greater bleeding control than non-clamping methods .
Three-hour interval drain clamping reduces postoperative bleeding in total knee arthroplasty: a prospective randomized controlled trial
Arch Orthop Trauma Surg. 2012 Jul;132(7):1059-63. doi: 10.1007/s00402-012-1501-z. Epub 2012 Mar 13100 patients who underwent uncomplicated total knee arthroplasty (TKA) were randomized to assess the efficacy of bleeding control for a clamping protocol compared to a non-clamping protocol. Patients received either non-clamping (where a vacuum drain was run continuously during the first postoperative day) or 3-hour interval clamping (where the vacuum was stopped twice for 3 hours each time). Results during the first 48 hours indicated that the drainage blood volume in the interval clamping group was significantly lower than the non-clamping group and that the mean hemoglobin fall at 12 hours was less in interval clamping group.
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