The disease-modifying effects of hyaluronan in the osteoarthritic disease state
OrthoEvidence Journal (OE Journal) - ACE Report
OE Journal. 2021;9(22):26 Clin Med Insights Arthritis Musculoskelet Disord. 2017;10:1-10What this means for my practice?
Although there are many molecules that will reduce the pain and inflammation due to OA, HA has the potential to reduce pain as well as to protect and restore the chondral matrix.
Study Summary
This review describes the etiology and pathophysiology of osteoarthritis (OA) and the role of hyaluronan (HA) in its progression. HAs antinociceptive and anti-inflammatory actions and disease modifying effects of the extracellular matrix (ECM) are further explored.
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