THA: Use of LIA or intrathecal morphine show no difference in occurrence of adverse events .
Local infiltration analgesia with levobupivacaine compared with intrathecal morphine in total hip arthroplasty patients
Acta Anaesthesiol Scand. 2012 Jul;56(6):695-705. doi: 10.1111/j.1399-6576.2012.02667.x. Epub 2012 Mar 760 patients undergoing total hip arthroplasty (THA) under spinal anesthesia were included in this study to compare the occurrence of adverse outcomes between two analgesic treatments. Patients were randomized to receive either local infiltration analgesia (LIA) or intrathecal morphine (it-M) after THA. When examined during the first 48 hours post-operatively, there was no significant difference in the occurrence of adverse events between LIA and it-M. Patients receiving LIA demonstrated slightly better early mobilization at 6 hours but this difference was not sustained at subsequent time points.
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