Three hundred and sixteen patients scheduled to undergo a total hip or knee arthroplasty were randomized to receive a pre-operative 15 min session of mind-body therapies including either mindfulness meditation (MM), hypnotic suggestion, or cognitive-behavioural (CB) pain psychoeducation. Outcomes of interest included pre-operative pain intensity, pain unpleasantness, anxiety, and pain medication desire measured on a numeric rating scale as well as self-reported physical function measured using the Patient-Reported Outcomes Measurement Information System Physical Function, at 6 weeks follow-up. Results of this trial revealed that pain intensity, pain unpleasantness, and anxiety were significantly lower in the MM group and hypnosis group when compared to the CB-pain group (p<0.05 for all). However, pain medication desire was only significantly lower in the MM group vs CB-pain group, whereas no significant difference was observed between the hypnosis and CB-pain group or MM vs hypnosis group (p>0.05). At 6 weeks follow-up, physical function was significantly improved in the MM group when compared to both the hypnosis and CB groups (p>0.05 for all).