Strontium ranelate improves radiological and clinical outcome in patients with knee OA .
This report has been verified
by one or more authors of the
original publication.
This study has been identified as potentially high impact.
OE's AI-driven High Impact metric estimates the influence a paper is likely to have by integrating signals from both the journal in which it is published and the scientific content of the article itself.
Developed using state-of-the-art natural language processing, the OE High Impact model more accurately predicts a study's future citation performance than journal impact factor alone.
This enables earlier recognition of clinically meaningful research and helps readers focus on articles most likely to shape future practice.
Efficacy and safety of strontium ranelate in the treatment of knee osteoarthritis: results of a double-blind, randomised placebo-controlled trial
Ann Rheum Dis. 2013 Feb;72(2):179-86. doi: 10.1136/annrheumdis-2012-202231. Epub 2012 Nov 1Exclusive Author Interview
Dr. Reginster discusses strontium ranelate effect the on radiological and clinical progression of knee osteoarthritis
1683 patients were randomized to assess the effect of strontium ranelate on radiological and clinical progression of knee osteoarthritis (OA). Patients received either strontium ranelate 1 g/day, 2 g/day, or placebo and were assessed over 3 years. Results revealed that treatment with strontium ranelate (1 and 2 g/day) was associated with a significant effect on structure in knee OA patients. Treatment with Strontium ranelate was associated with smaller degradations of joint space width compared to placebo. Additionally, a beneficial effect was observed on pain and function for patients receiving the treatment 2 g/day.
Unlock the Full ACE Report
You have access to 4 more FREE articles this month.
Click below to unlock and view this ACE Reports
Unlock Now
Critical appraisals of the latest, high-impact randomized controlled trials and systematic reviews in orthopaedics
Access to OrthoEvidence podcast content, including collaborations with the Journal of Bone and Joint Surgery, interviews with internationally recognized surgeons, and roundtable discussions on orthopaedic news and topics
Subscription to The Pulse, a twice-weekly evidence-based newsletter designed to help you make better clinical decisions
Exclusive access to original content articles, including in-house systematic reviews, and articles on health research methods and hot orthopaedic topics
Or upgrade today and gain access to all OrthoEvidencecontent for as little as $1.99 per week.
Already have an account? Log in
0 of 4 monthly FREE articles unlocked
