Association of Spinal Manipulative Therapy With Clinical Benefit and Harm for Acute Low Back Pain: Systematic Review and Meta-analysis

This report has been verified by one or more authors of the original publication.

この研究はハイインパクトの可能性があります。 OEのAI駆動型ハイインパクト指標は、論文が掲載されたジャーナルと論文自体の科学的内容の両方からのシグナルを統合することで、論文が持つ可能性の高い影響力を推定します。 最先端の自然言語処理を用いて開発されたOEハイインパクトモデルは、ジャーナルのインパクトファクターのみよりも、研究の将来の引用実績をより正確に予測します。 これにより、臨床的に意義のある研究をより早く認識することが可能になり、読者は将来の診療を形成する可能性が最も高い論文に集中することができます。

Twenty-six (26) randomized controlled trials were included in this systematic review and meta-analysis evaluating the efficacy of spinal manipulative therapy (SMT) compared to either active control comparators or sham treatment in the management of acute low back pain. Observational studies were also included to evaluate the safety of SMT. Results demonstrated significant effects in favour of SMT at 3-6 weeks for both pain and function. Eight of the 26 RCTs from the efficacy analyses were included in comparison of adverse events, and complemented by another 3 RCTs and 5 prospective cohort studies which only reported data on adverse events. There was high-quality evidence that transient musculoskeletal pain adverse events may be experienced following SMT, though a few studies which compared rates between treatment groups suggested similar incidences between manual therapy with and without SMT, or between SMT and sham treatment. No serious adverse events were reported among RCTs.