HAND & WRIST
Prospective randomized comparison of single-incision and two-incision carpal tunnel release outcomes
This report has been verified
by one or more authors of the
original publication.
OrthoEvidence Journal (OE Journal) - ACE Report
OE Journal. 2014;2(10):19 Hand (N Y). 2014 Mar;9(1):36-42. doi: 10.1007/s11552-013-9572-z.Exclusive Author Interview
Dr. J. Yao discusses a prospective randomized comparison of single-incision and two-incision carpal tunnel release
30 patients with carpal tunnel syndrome were randomized to undergo single- or two-incision carpal tunnel release to compare clinical and functional outcomes between surgical techniques. Upon analysis, results revealed no significant difference between groups with respect to the Disabilities of the Arm, Shoulder, and Hand (DASH) Questionnaire, Brigham and Womens Carpal Tunnel Questionnaire (BWCTQ) for symptom severity and functional status, grip strength, pinch strength, scar tenderness, or radial and ulnar pillar pain. The single-incision group demonstrated improved Semmes-Weinstein monofilament scores in the second finger at 6 weeks and third finger at 6+ months postoperatively when compared to the two-incision group.
Was the allocation sequence adequately generated?
Was allocation adequately concealed?
Blinding Treatment Providers: Was knowledge of the allocated interventions adequately prevented?
Blinding Outcome Assessors: Was knowledge of the allocated interventions adequately prevented?
Blinding Patients: Was knowledge of the allocated interventions adequately prevented?
Was loss to follow-up (missing outcome data) infrequent?
Are reports of the study free of suggestion of selective outcome reporting?
Were outcomes objective, patient-important and assessed in a manner to limit bias (ie. duplicate assessors, Independent assessors)?
Was the sample size sufficiently large to assure a balance of prognosis and sufficiently large number of outcome events?
Was investigator expertise/experience with both treatment and control techniques likely the same (ie.were criteria for surgeon participation/expertise provided)?
はい = 1
不確実＝0.5
無関係 = 0
いいえ = 0
報告基準評価では、著者が出版物内で試験の方法論的特徴や試験特性を報告する際の透明性を評価します。評価は以下の5つのカテゴリーに分類されます。
3/4
Randomização
2/4
Medidas de resultado
4/4
Inclusão/Exclusão
4/4
Descrição do tratamento
4/4
Estatística
Detsky AS, Naylor CD, O'Rourke K, McGeer AJ, L'Abbé KA. J Clin Epidemiol. 1992;45:255-65
Fragility Indexは、重要な所見の解釈を助けるツールで、結果の強さの尺度を提供します。Fragility Indexは、その所見が有意でなくなるために、二項対立の結果に追加する必要がある連続した事象の数を表します。数値が小さいほど弱い所見を表し、数値が大きいほど強い所見を表します。
なぜ今この研究が必要なのですか？
Carpal tunnel release (CTR) is one of the most common surgical procedures performed in the United States. During CTR, the complete division of the flexor retinaculum is standard clinical practice, but the optimal CTR technique itself remains arguable. Previously, the authors conducted a retrospective study that reported improved function and fewer postoperative symptoms in patients that received a two-incision approach compared to single-incision technique. This randomized control trial was needed to further prospectively evaluate qualitative and quantitative postoperative outcomes between single- and two-incision CTR.
主な研究課題は何ですか？
Is single or two-incision carpal tunnel release more efficacious for treating patients with carpal tunnel syndrome, assessed up to 6+ months postoperatively?
重要な知見は？
- BWCTQ symptom severity scale (SSS), BWCTQ functional status scale (FSS), DASH scores, grip strength, and pinch strength did not differ significantly between the single- and two-incision groups at any follow-up time point (all p>0.05).
- The two incision group reduced scar tenderness, radial pillar pain, and ulnar pillar pain, although this did not reach statistical significance at any time point when compared to the single-incision group (all p>0.05). At 6+ months follow-up, no patients in the two-incision group reported scar tenderness or pillar pain.
- Semmes-Weinstein monofilament scores (measured thumb, second finger, third finger) demonstrated significantly more improvement in the single-incision group compared to the two-incision group in the second finger at 6 weeks (p=0.03) and third finger at 6 months postoperatively (p=0.04). No other statistically significant differences were observed in any finger at any other time point (p>0.05).
- A statistically significant positive correlation was observed between pre-and post-operative FSS and DASH scores in both groups (p<0.0001). A statistically significant negative correlation was observed between pre-operative and 2 week postoperative grip and pinch strength and DASH scores but these findings lost statistical significance by 6 week and 6+ month time points, with the exception of grip and pinch strength ((R= -0.80, p <0.0001) and DASH scores (R= -0.83, p <0.0001) in the single-incision group at 6+ months postoperative.
最も覚えておくべきことは？
The single-incision and two-incision techniques for carpal tunnel release were similar at 2 weeks, 6 weeks, and 6+ months postoperative with respect to Disabilities of the Arm, Shoulder, and Hand (DASH) Questionnaire, Brigham and Women's Carpal Tunnel Questionnaire (BWCTQ) for symptom severity and functional status, grip strength, and pinch strength. Less scar tenderness, and radial and ulnar pillar pain was reported in the two-incision group, although this finding did not reach statistical significance. Improved Semmes-Weinstein monofilament scores were observed in the single-incision group in the second finger at 6 weeks and third finger at 6+ months postoperative.
それが私の患者ケアにどのように影響するか？
Based on the results of this study, both the single- and two-incision carpel tunnel release techniques may be offered as equally efficacious treatments for patients with carpel tunnel syndrome. Future studies with larger cohorts and less patient drop-out should compare the aforementioned findings between surgical techniques. It may also be advantageous to conduct a cost-comparison between treatment groups.
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