Efficacy of Ultrasound-guided Intra-articular Injections of Platelet-rich Plasma Versus Hyaluronic Acid for Hip Osteoarthritis
OrthoEvidence Journal (OE Journal) - ACE Report
OE Journal. 2020;8(14):19 Orthopedics. 2013 Dec;36(12):e1501-8.What this means for my practice?
Results of the study suggest that PRP and HA injections provide similar clinical improvement in patients with hip OA but no differences were detected between the two groups. However, there are limitations with this study including that the PRP treatment group had significantly younger patients, and a greater baseline of NSAID consumption when compared to the HA group.
Study Summary
One hundred patients with hip osteoarthritis (OA) were randomized to receive 3 consecutive injections of autologous platelet-rich plasma (PRP) or hyaluronic acid (HA) once every two weeks. The outcomes of interest included the Harris Hip Score (HHS), pain on a Visual Analog Scale (VAS) as well as non-steroidal anti-inflammatory drug (NSAID) consumption. Outcomes were assessed at 1, 3, 6, and 12 months post-treatment. Results revealed no significant differences in HHS and VAS pain scores at all time points between PRP and HA treatments; however, a significant improvement was found for both groups at follow-up of 1-3 months. Also, NSAID consumption was significantly reduced over time in both groups.
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