Similar changes in clinical & radiographic results after 2 years with IA steroid vs saline .
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Safety and efficacy of long-term intraarticular steroid injections in osteoarthritis of the knee: a randomized, double-blind, placebo-controlled trial
Arthritis Rheum. 2003 Feb;48(2):370-7
68 patients with knee osteoarthritis were randomized to be administered intra-articular injections of triamcinolone acetonide (IA corticosteroid) or saline (IA saline) every 3 months for 2 years. The purpose of this study was to compare patient-reported pain, stiffness, and function, patient's and physician global assessment of improvement, knee range of motion, and radiographic joint space narrowing between groups after 1 and 2 years. No significant between-group differences were observed for the change in any outcome measure after 1 or 2 years.
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