Similar 3-month efficacy for single-injection corticosteroid & hyaluronic acid in knee OA .
Hyaluronic acid compared with corticosteroid injections for the treatment of osteoarthritis of the knee: a randomized control trial
Springerplus. 2016 Apr 12;5:442140 patients with Kellgren-Lawrence grade II-III knee osteoarthritis were randomized to a single intra-articular injection of either corticosteroid or hyaluronic acid. The purpose of this study was to compare clinical outcome measures (VAS pain; WOMAC; KOOS) between groups at 1, 2, and 3 months post-injection. The only significant difference between groups observed was significantly lower VAS pain in the CS group compared to the HA group at 1 month. All other measures at all time points demonstrated no significant difference between groups.
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