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Shoulder pain: Pain and function significantly improved with image-guided injection
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SHOULDER & ELBOW

Image-guided versus blind corticosteroid injections in adults with shoulder pain: a systematic review

OrthoEvidence Journal (OE Journal) - ACE Report

OE Journal. 2014;2(5):28 BMC Musculoskelet Disord. 2011 Jun 25;12:137. doi: 10.1186/1471-2474-12-137

Autores contribuintes

E Soh W Li KO Ong W Chen D Bautista

Findings of two randomized controlled trials were pooled in order to investigate if method of corticosteroid injection - either image-guided or anatomical landmark guided (blind) - impacted clinical outcome in patients suffering from shoulder pain. Clinical outcomes of pain and function were reported at 6 weeks, and the incidences of adverse events were recorded. Pooled effects illustrated that pain and function at 6 weeks were significantly improved with image-guided injections compared to blind injections. Incidence of adverse events was also lower in image-guided group; however, the difference did not reach statistical significance.


Detalhes do financiamento da publicação +
Financiamento:
Not Reported
Conflitos:
Other

Risco de viés

9,5/10

Critérios de notificação

17/20

Índice de Fragilidade

N/A

Were the search methods used to find evidence (original research) on the primary question or questions stated?

Was the search for evidence reasonably comprehensive?

Were the criteria used for deciding which studies to include in the overview reported?

Was the bias in the selection of studies avoided?

Were the criteria used for assessing the validity of the included studies reported?

Was the validity of all of the studies referred to in the text assessed with use of appropriate criteria (either in selecting the studies for inclusion or in analyzing the studies that were cited)?

Were the methods used to combine the findings of the relevant studies (to reach a conclusion) reported?

Were the findings of the relevant studies combined appropriately relative to the primary question that the overview addresses?

Were the conclusions made by the author or authors supported by the data and or analysis reported in the overview?

How would you rate the scientific quality of this evidence?

Sim = 1

Incerto = 0,5

Não relevante = 0

Não = 0

A Avaliação dos Critérios de Relato avalia a transparência com que os autores relatam as caraterísticas metodológicas e do ensaio na publicação. A avaliação está dividida em cinco categorias que são apresentadas de seguida.

4/4

Introduction

4/4

Accessing Data

4/4

Analysing Data

2/4

Results

3/4

Discussion

Detsky AS, Naylor CD, O'Rourke K, McGeer AJ, L'Abbé KA. J Clin Epidemiol. 1992;45:255-65

O Índice de Fragilidade é uma ferramenta que auxilia na interpretação de achados significativos, fornecendo uma medida de força para um resultado. O Índice de Fragilidade representa o número de eventos consecutivos que precisam de ser adicionados a um resultado dicotómico para que o resultado deixe de ser significativo. Um número pequeno representa um resultado mais fraco e um número grande representa um resultado mais forte.

Porque é que este estudo era necessário agora?

Shoulder pain of a number of etiologies is commonly treated with injection of corticosteroid. Injections can be performed "blindly", using anatomical landmarks for guidance, or image guidance can be used for guidance, usually with ultrasound. Although studies have reported that image guidance does lead to higher injection accuracy, there are conflicting reports about whether or not higher accuracy is translated into more improved outcome compared to blind injection. Therefore, this study was designed to assess clinical outcome of patients treated with either blind or image-guided injection.

Qual era a principal questão de investigação?

Did image-guided injection of corticosteroid lead to improved clinical outcome, primarily pain, and function when compared to landmark-guided injection?

Caraterísticas do estudo +
Fonte de dados:
A search for articles published up to May 2010 was conducted of the electronic databases MEDLINE, EMBASE, and the Cochrane Controlled Trials Register. Bibliographies of pertinent articles were also searched for additional studies.
Termos do índice:
Keyword terms included: "blind", "landmark", "anatomical", "clinical exam", "image-guided", "ultrasound", "fluoroscopy", "steroid injection", "frozen shoulder", "random allocation", "randomized controlled trial", and "clinical trial"
Seleção do estudo:
Studies were selected under the criteria that they were randomized controlled trials that compared single corticosteroid injections guided by anatomical landmarks versus ultrasound- or fluoroscopy-guided injection in shoulder pain treatment. Studies also had to assess pain on a visual analog scale, and function on a validated scale, such as the Constant Score. Selection was performed by three authors, and decision for inclusion was made by all three reviewers.
Extração de dados:
Data extraction was performed independently by two authors according to a predefined data extraction table.
Síntese de dados:
Data was pooled using Review Manager software (RevMan v5.0). Standardized mean differences (SMD) were calculated for pain and function scores, and risk ratios (RR) were used for safety analyses of adverse events. Heterogeneity was assessed using the I^2 statistic and the chi-square-based test. Pooling was made under the random effects model.

Quais foram os resultados importantes?

  • Two studies were selected for inclusion, both of which reported pain, function, and adverse events experienced.
  • Pain outcome (VAS 0-10) at 6 weeks was significantly improved with image-guided injection compared anatomical landmark guidance (SMD 2.23 (95%CI 1.27-3.18), p<0.00001) (I-squared = 61%).
  • Functional outcome was assessed by either the Constant Score of the Shoulder Function Assessment Scale. Pooled effect resulted in significant improvement at 6 weeks with the use of image guidance compared to blind injection (SMD 1.09 (0.61-1.57), p<0.00001) (I-squared = 22%).
  • Incidence of mild adverse events was lower when image-guided injection was performed (RR 0.20 (0.04-1.13)), however the difference did not reach statistical significance (p=0.07). Heterogeneity was not observed (I-squared = 0%). Time-frame of which adverse events were recorded was not reported.
De que é que me devo lembrar mais?

Image-guidance of corticosteroid injection in shoulder pain treatment was associated with a significant improvement in pain and function at 6 weeks compared to blind injection. A lower incidence of adverse events was also associated with image-guided injection, however the difference was not statistically significant.

Como é que isto afectará o tratamento dos meus doentes?

The findings of this analysis suggest that improved clinical outcomes may be attained with an ultrasound- or fluoroscopy-guided injection of corticosteroid when treating shoulder pain. Since the number of studies included in this analysis was rather low (only 2), as well the noted heterogeneity in the pain outcome analysis, more trials investigating this comparison are needed to either substantiate or refute these findings, and to ultimately conclude on injection guidance efficacy.

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OrthoEvidence. Shoulder pain: Pain and function significantly improved with image-guided injection. OE Journal. 2014;2(5):28. Available from: https://myorthoevidence.com/AceReport/Show/shoulder-pain-pain-and-function-significantly-improved-with-image-guided-injection

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