Safety and Efficacy of Tranexamic Acid in Patients Undergoing Thoracic Spine Stenosis Surgery .
The efficacy and safety of intravenous tranexamic acid in patients with posterior operation of multilevel thoracic spine stenosis: a prospective randomized controlled trial
BMC Musculoskelet Disord . 2022 May 2;23(1):410.Sixty-eight patients who were undergoing surgery for multilevel thoracic spine stenosis were randomized to receive tranexamic acid (TXA) or placebo during their surgery. The primary outcomes of this trial were to determine the total blood lost intraoperatively and perioperatively. Other outcomes such as the need for a blood transfusion, blood coagulation function, and length of hospital stay were also assessed. The results of this trial showed significant reductions in intraoperative and perioperative blood loss as well as the need for a blood transfusion in the TXA group.
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