Routine thromboprophylaxis appears unnecessary following knee arthroscopy and lower-leg casting .
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Thromboprophylaxis after Knee Arthroscopy and Lower-Leg Casting.
N Engl J Med. 2017 Feb 9;376(6):515-525.1543 patients undergoing knee arthroscopy (POT-KAST trial) and 1519 patients undergoing casting of the lower leg (POT-CAST trial) were randomized to receive or not anticoagulant therapy. The aim of these studies was to examine the efficacy of thromboprophylaxis in these groups of patients. The result of these trials indicated that the use of low-molecular-weight heparin did not reduce the rate of symptomatic venous thromboembolism in either patient population compared to no anticoagulant treatment.
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