161 patients presenting to the emergency department with a hip fracture were randomized to administration of a femoral nerve block in the ED followed by a fascia iliac block within 24 hours, or to standard intravenous and oral analgesia during the perioperative stay. Patients were followed up for preoperative and postoperative pain, opioid consumption, functional ability, and the incidence of opioid-related adverse events up to 3 days postoperatively. Results demonstrated that the peripheral nerve block regimen was associated with significantly lower pain scores and analgesic requirement preoperatively and after 3 days postoperatively, as well as a longer distance walked over a 2 minute period on the third postoperative day when compared to standard oral and IV analgesics.