Analysis for prognostic factors from a database for the intra-articular hyaluronic acid (Euflexxa) treatment for osteoarthritis of the knee
OrthoEvidence Journal (OE Journal) - ACE Report
OE Journal. 2021;9(22):23 Cartilage. 2016 Jul;7(3):229-37.What this means for my practice?
Patients with K-L grade 2 knee OA had greater positive response to IA-HA treatment, when compared with K-L grade 3 patients.
Study Summary
Patients’ data from the FLEXX trial and its subsequent extension trial were analyzed to identify factors associated with effects of intra-articular injection of hyaluronic acid (IA-HA) among patients with knee osteoarthritis (OA). Poorer baseline characteristics of patients, including higher pain score, higher WOMAC subscales, and Kellgren Lawrence (K-L) grade 3 were associated with worse outcomes.
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