Clinical and radiographic analysis of an artificial cervical disc: 7-year follow-up from the Prestige prospective randomized controlled clinical trial

This report has been verified by one or more authors of the original publication.

この研究はハイインパクトの可能性があります。 OEのAI駆動型ハイインパクト指標は、論文が掲載されたジャーナルと論文自体の科学的内容の両方からのシグナルを統合することで、論文が持つ可能性の高い影響力を推定します。 最先端の自然言語処理を用いて開発されたOEハイインパクトモデルは、ジャーナルのインパクトファクターのみよりも、研究の将来の引用実績をより正確に予測します。 これにより、臨床的に意義のある研究をより早く認識することが可能になり、読者は将来の診療を形成する可能性が最も高い論文に集中することができます。

541 patients diagnosed with single-level cervical disc disease with radiculopathy were randomized to either undergo anterior cervical discectomy and fusion (ACDF) or cervical disc arthroplasty (CDA) with the Prestige Cervical Disc. The purpose was to investigate the long-term efficacy and safety of cervical disc replacement with the Prestige prosthesis up to 7 years postoperatively. Results revealed that CDA allowed a statistically significant greater percentage of patients to achieve "overall success" at 84 months, which was defined as a minimum 15-pt increase on the Neck Disability Index, maintained or improved neurological status, no implant- or surgical procedure-related serious adverse event, and no failure requiring further additional surgical procedures. A secondary analysis was also performed which included maintained disc height as a parameter of clinical success, which maintained significant difference between groups at 84 months.