Efficacy of platelet-rich plasma injections in osteoarthritis of the knee: a systematic review and meta-analysis

This report has been verified by one or more authors of the original publication.

この研究はハイインパクトの可能性があります。 OEのAI駆動型ハイインパクト指標は、論文が掲載されたジャーナルと論文自体の科学的内容の両方からのシグナルを統合することで、論文が持つ可能性の高い影響力を推定します。 最先端の自然言語処理を用いて開発されたOEハイインパクトモデルは、ジャーナルのインパクトファクターのみよりも、研究の将来の引用実績をより正確に予測します。 これにより、臨床的に意義のある研究をより早く認識することが可能になり、読者は将来の診療を形成する可能性が最も高い論文に集中することができます。

6 randomized controlled trials (RCTs) and 4 non-randomized clinical trials with a total of 1110 patients were included in this systematic review and meta-analysis to determine the effectiveness of platelet-rich plasma (PRP) injections in patients with osteoarthritis (OA) of the knee. Results demonstrated a significant reduction in pain in patients treated with PRP compared to patients treated with placebo or hyaluronic acid injections. Additionally, WOMAC physical function was also seen to significantly favor PRP treatment in comparison to the placebo and hyaluronic acid injection groups. Results from the systematic review and meta-analysis should be interpreted with caution as the majority of the trials included were associated with a high risk of bias and there was significant heterogeneity in the outcomes assessed.