Perioperative NSAIDs on Pain & Opioid Consumption After Spine Surgery: A Meta-Analysis .
The impact of perioperative nonsteroidal anti-inflammatory drugs on the postoperative outcomes of spinal surgery: a meta-analysis of 23 randomized controlled trials.
Neurosurg Rev . 2024 Apr 5;47(1):140.Twenty-three randomized controlled trials including 1457 patients undergoing spinal surgery were included in this systematic review and meta-analysis comparing the perioperative use of NSAIDs vs. no NSAIDs. Pooled outcomes of interest included postoperative morphine consumption and pain scores. The meta-analysis showed that NSAIDs significantly reduced postoperative morphine use and pain scores. The findings suggest that perioperative NSAIDs are beneficial in managing postoperative pain and reducing opioid consumption in spinal surgery patients.
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