Pamidronate reduces femoral calcar bone loss, bone turnover after THA .
Effect of pamidronate on bone turnover and implant migration after total hip arthroplasty: A randomized trial
J Orthop Res. 2005 Jan;23(1):1-8.42 patients who have undergone total hip arthroplasty were randomized to receive pamidronate or a placebo to determine the effect of pamidronate on periprosthetic bone turnover and pelvic implant migration. The results of the study indicated that pamidronate reduced femoral calcar bone loss and bone turnover, but did not influence cup migration.
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