Painful Vs. Pain-Free Manual Therapy for Non-Specific Neck Pain .
Manual Therapy Effects on Nonspecific Neck Pain Are Not Mediated by Mechanisms Related to Conditioned Pain Modulation: A Randomized Clinical Trial.
J Clin Med. 2023 Jun 7;12(12):3894.Thirty-eight patients with chronic or recurrent nonspecific neck pain were randomized to receive either painful manual therapy (MT) (n=19) or pain-free manual therapy (n=19). Outcomes of interest included pressure pain thresholds (PPT), conditioned pain modulation (CPM), temporal summation of pain (TSP), cold pain intensity, intensity of neck pain, expectations, and self-perceived improvement by Global Rating of Change (GROC). No significant differences were apparent between the two groups for all outcome measures except for pain intensity compared to baseline. Change from baseline pain intensity was significantly better in the pain-free MT group. Additionally, positive expectations were significantly higher in the painful MT group.
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