OTA2017: No impact of alendronic acid on union rate following distal radius fracture .
The FaB (Fractures and Bisphosphonates) Trial: A Multicenter, Double-Blind, Randomized Controlled Trial on the Effect of Alendronic Acid on Healing and Clinical Outcomes of Wrist Fractures
421 patients, 50 years of age or older, with an acute distal radius fracture, were randomized to weekly alendronic acid or placebo. Patients were assessed for union rate at scheduled follow-up. No significant differences between groups were observed in union rates after 4 weeks, 6 weeks, or 2 months.
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