Oral tranexamic acid is safe and effective in reducing post-operative blood loss in TKA .
This report has been verified
by one or more authors of the
original publication.
Effectiveness of oral Tranexamic acid administration on blood loss after knee artroplasty: a randomized clinical trial
Transfus Apher Sci. 2013 Dec;49(3):574-7. doi: 10.1016/j.transci.2013.09.005. Epub 2013 Oct 553 patients scheduled to undergo total knee arthroplasty (TKA) were randomized to either receive or not receive oral administration of tranexamic acid. The purpose was to determine whether this intervention was safe and effective in reducing the amount of postoperative blood loss. Results indicated that the tranexamic acid group displayed significantly better hematocrit levels post-operation and significantly lower bleeding rates 12 and 24 hours post-surgery. At 6 weeks postoperatively, there were no reported thrombotic complications in either group.
Unlock the Full ACE Report
You have access to 4 more FREE articles this month.
Click below to unlock and view this ACE Reports
Unlock Now
Critical appraisals of the latest, high-impact randomized controlled trials and systematic reviews in orthopaedics
Access to OrthoEvidence podcast content, including collaborations with the Journal of Bone and Joint Surgery, interviews with internationally recognized surgeons, and roundtable discussions on orthopaedic news and topics
Subscription to The Pulse, a twice-weekly evidence-based newsletter designed to help you make better clinical decisions
Exclusive access to original content articles, including in-house systematic reviews, and articles on health research methods and hot orthopaedic topics
Or upgrade today and gain access to all OrthoEvidencecontent for as little as $1.99 per week.
Already have an account? Log in
0 of 4 monthly FREE articles unlocked
