Oral supplement improves repair integrity and reduces pain after rotator cuff repair .
Arginine L-alpha-ketoglutarate, methylsulfonylmethane, hydrolyzed type I collagen and bromelain in rotator cuff tear repair: A prospective randomized study
Curr Med Res Opin. 2012 Nov;28(11):1767-74. doi: 10.1185/03007995.2012.737772. Epub 2012 Oct 1990 patients with large, postero-superior rotator cuff tears were randomized to receive a supplement (containing arginine L-alpha-ketoglutarate, methylsulfonylmethane, hydrolyzed type I collagen and bromelain) or no supplement. Over 12 months, there was no difference between the two groups for clinical scores, rate of re-rupture, and fatty degeneration grade. However, the supplement group experienced significantly less shoulder pain than the control group at 6 months. Additionally, a larger proportion of patients in the supplement group had better repair integrity results.
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