Optimized Tourniquet Use in Primary Total Knee Arthroplasty: A Comparative, Prospective, and Randomized Study.

この研究はインパクトが大きい可能性があると判断されました。 OEのAIによるハイインパクト指標は、論文が掲載されたジャーナルと論文自体の科学的内容の両方からのシグナルを統合することで、論文の影響力を推定します。 最先端の自然言語処理を用いて開発されたOEハイインパクトモデルは、ジャーナルのインパクトファクターのみよりも、研究の将来の引用実績をより正確に予測します。 これにより、臨床的に意義のある研究をより早く認識することができ、読者は将来の診療を形成する可能性が最も高い論文に焦点を当てることができます。

研究概要

130 patients with knee osteoarthritis undergoing a total knee arthroplasty procedure were randomized to receive optimized tourniquet use (n=65) or no tourniquet (n=65) during the procedure. For the tourniquet group, inflation pressure was set at 100mmHg above systolic blood pressure, applied after exsanguination of the limb with a crepe bandage and prior to skin incision, and removed immediately after fixation of the prosthesis to the bone with cement. Outcomes of interest included blood loss, hemoglobin levels, pain in the knee and thigh, lower limb circumference as a measure of swelling, range of motion, Knee Society Score (KSS), the straight leg test, and complications. Follow-up was up to 6 months post-operation. The optimized tourniquet use and the no tourniquet group had similar blood loss, operative time, pain or swelling, functional scores, and complication rate, with the exception of range of motion which was significantly better in the tourniquet group at 3 weeks. Given the benefits of tourniquet use with respect to providing a clear surgical field, this optimized tourniquet protocol is a promising solution to minimize the tourniquet-related adverse events often reported. However, future studies with longer follow-ups and a wider range of patients are necessary to confirm the results.