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Operative care of clavicle fracture reduces complications, nonunion, and malunion
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TRAUMA
Operative care of clavicle fracture reduces complications, nonunion, and malunion .

OrthoEvidence Journal (OE Journal) - ACE Report

OE Journal. 2013;1(16):49 Int Orthop. 2013 Aug;37(8):1495-500
Autores colaboradores

GD Liu SL Tong S Ou LS Zhou J Fei GX Nan JW Gu

5 randomized clinical trials and 3 controlled clinical trials (663 patients) were examined in this meta-analysis to determine if operative treatment provides better results than nonoperative treatment of clavicle fractures. The results from this meta-analysis suggest that operative care was associated with a reduced risk of non-union, malunion, and fewer neurological complications compared to nonoperative care. Statistical analysis of functional outcomes and long term adverse effects could not be completed due to incomplete reporting. However, qualitative assessment indicated that Constant Shoulder Scores and DASH scores were superior in the operative group.


Detalles de la financiación de la publicación +
Financiación:
Non-Industry funded
Patrocinador:
National Natural Science Foundation of China; Military Twelfth Five Key Projects; Foundation of State Key Laboratory of Trauma, Burns and Combined Injuries
Conflicts:
None disclosed

Riesgo de sesgo

10/10

Criterios de información

18/20

Índice de fragilidad

N/A

Were the search methods used to find evidence (original research) on the primary question or questions stated?

Was the search for evidence reasonably comprehensive?

Were the criteria used for deciding which studies to include in the overview reported?

Was the bias in the selection of studies avoided?

Were the criteria used for assessing the validity of the included studies reported?

Was the validity of all of the studies referred to in the text assessed with use of appropriate criteria (either in selecting the studies for inclusion or in analyzing the studies that were cited)?

Were the methods used to combine the findings of the relevant studies (to reach a conclusion) reported?

Were the findings of the relevant studies combined appropriately relative to the primary question that the overview addresses?

Were the conclusions made by the author or authors supported by the data and or analysis reported in the overview?

How would you rate the scientific quality of this evidence?

Sí = 1

Incierto = 0,5

No relevante = 0

No = 0

La evaluación de los criterios de información evalúa la transparencia con la que los autores informan de las características metodológicas y del ensayo dentro de la publicación. La evaluación se divide en cinco categorías que se presentan a continuación.

4/4

Introduction

4/4

Accessing Data

4/4

Analysing Data

3/4

Results

3/4

Discussion

Detsky AS, Naylor CD, O'Rourke K, McGeer AJ, L'Abbé KA. J Clin Epidemiol. 1992;45:255-65

El Índice de Fragilidad es una herramienta que ayuda en la interpretación de hallazgos significativos, proporcionando una medida de fuerza para un resultado. El Índice de Fragilidad representa el número de eventos consecutivos que es necesario añadir a un resultado dicotómico para que el hallazgo deje de ser significativo. Un número pequeño representa un hallazgo más débil y un número grande un hallazgo más fuerte.

¿Por qué se necesitaba ahora este estudio?

Clavicle fractures are an exceedingly common injury in adults. Until recently these injuries tended to be treated through nonoperative means. However, recent research has indicated that operative care may potentially result in fewer nonunions, malunions, delayed unions and neurological complications, while providing superior functional outcomes. This meta-analysis and systematic review aims to provide an update to current assessments in the literature.

¿Cuál era la pregunta principal de la investigación?

Does operative treatment of a fractured clavicle provide better clinical and functional outcomes compared to nonoperative treatment involving a sling or bandage?

Características del estudio +
Data Source:
Online sources include MEDLINE, Embase, OVID, relevant articles from Google Scholar and the Cochrane Central Register of Controlled Trials up to December 2011
Index Terms:
Clavicle and fractures and (randomized controlled trial OR controlled clinical trial)
Study Selection:
Studies were included if they were randomized control trials or clinical control trials; provided a definite study period, sample size, and pathological diagnostic criteria; used operative and nonoperative therapeutic methods; performed high quality data collection; and compared CS, DASH score, nonunion, delayed union and complication outcomes. Studies were excluded if the sample size, grouping, pathological diagnostic criteria, control design and control source were undefined; non-therapeutic clinical studies or animal experiments were used; fracture not due to trauma, unscientific data collection was performed, no therapeutic outcome and review literature, retrospective studies and repeated reports.
Data Extraction:
Outcome data from the studies included in this meta-analysis was extracted by two authors independently.
Data Synthesis:
The statistical analysis of this data was completed with Review Manager 5.0 software. Continuous data and dichotomous data both had a 95% confidence interval and were organized as standardized mean differences and risk ratios respectively. Significantly heterogeneous (p>0.5) data was pooled with a random-effects model; non-significant heterogeneous data was pooled with a fixed-effects model.
¿Cuáles fueron los hallazgos importantes?
  • 8 studies (I^2 = 0%) involving 566 patients indicated a reduced risk of nonunion for operative treatment compared to nonoperative (RR 0.12, 95 % CI 0.05-0.29) (p<0.0001).
  • 6 homogeneous (I^2 = 0%) studies with 453 patients indicated a decreased risk of malunion in the operative treatment (RR 0.11, 95 % CI 0.04-0.29) (p<0.0001).
  • 5 studies (I^2 = 29%) (337 patients) found no significant difference in the delayed union rates (RR 0.78, 95 % CI 0.31-1.95) (p=0.59).
  • 7 studies (I^2 = 28%) (468 patients) showed fewer neurological complications associated with operative treatment (RR 0.45, 95 % CI 0.25-0.80) (p=0.008).
  • A meta-analysis could not be competed on the CS and DASH scores due to incomplete reporting of standard deviation. A qualitative assessment of CS scores from 5 studies and DASH scores from 4 studies indicated superior results for operative treatment of clavicle fractures.
¿Qué es lo que más debo recordar?

This meta-analysis supports operative measures for the treatment of a fractured clavicle based on reduced rates of nonunion, malunion and neurological complications. However, it should be noted that the functional outcomes examined (CS and DASH scores) were not included in the meta-analysis. Qualitative assessment of these outcomes indicated that operative treatment may provide superior function.

¿Cómo afectará esto al cuidado de mis pacientes?

Operative care of clavicle fractures effectively reduced the risks of non-union, malunion and neurological complications compared to non-operative treatment. Further research still needs to be conducted to identify specifically which types of clavicle fractures benefit the most from surgical fixation. Finally, treatment should be left to the discretion of the treating physician and patient preference.

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OrthoEvidence. Operative care of clavicle fracture reduces complications, nonunion, and malunion. OE Journal. 2013;1(16):49. Available from: https://myorthoevidence.com/AceReport/Show/operative-care-of-clavicle-fracture-reduces-complications-nonunion-and-malunion

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