Eighty-six patients with patellofemoral pain syndrome were randomized to receive either supervised therapeutic exercise (n=43) or a combination of radiofrequency diathermy with supervised therapeutic exercise (n=43). The primary outcome of interest was knee pain intensity, while secondary outcomes included knee function (measured by the Kujala and LEFS scores), range of knee motion, and overall quality of life. Outcomes were assessed at baseline, after the final treatment session, and at six months. Overall, results indicated that the group receiving RFD alongside TE showed significantly greater improvements in pain and function scores compared to the TE-only group. These findings suggest that adding RFD to therapeutic exercises enhances the effectiveness of exercise alone in managing patellofemoral pain, with benefits sustained over six months.