No significant effect of fibrin sealant on postoperative function following total knee arthroplasty .
The effect of a fibrin sealant on knee function after total knee replacement surgery. Results from the FIRST trial. A multicenter randomized controlled trial
PLoS One. 2018 Jul 25;13(7):e0200804. doi: 10.1371/journal.pone.0200804498 patients scheduled for total knee arthroplasty were randomized to either intraoperative fibrin sealant application or to no additional fibrin sealant. Patients were assessed for the primary outcome of change in knee extension angle after 2 weeks. Among secondary outcomes included the change in knee flexion angle, length of hospital stay, and incidence of complications. Results demonstrated no significant difference between the fibrin sealant and control group for either improvement in knee extension angle, improvement in knee flexion angle, length of hospital stay, or incidence of complications.
Unlock the Full ACE Report
You have access to 4 more FREE articles this month.
Click below to unlock and view this ACE Reports
Unlock Now
Critical appraisals of the latest, high-impact randomized controlled trials and systematic reviews in orthopaedics
Access to OrthoEvidence podcast content, including collaborations with the Journal of Bone and Joint Surgery, interviews with internationally recognized surgeons, and roundtable discussions on orthopaedic news and topics
Subscription to The Pulse, a twice-weekly evidence-based newsletter designed to help you make better clinical decisions
Exclusive access to original content articles, including in-house systematic reviews, and articles on health research methods and hot orthopaedic topics