No significant difference between Dabigatran etexilate and enoxaparin in VTE occurrence .
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Dabigatran etexilate versus enoxaparin for prevention of venous thromboembolism after total hip replacement: a randomised, double-blind, non-inferiority trial
Lancet. 2007 Sep 15;370(9591):949-563494 patients undergoing total hip replacement were randomized to either receive 220mg of Dabigatran etexilate, 150mg of Dabigatran etexilate, or enoxaparin. The results following the treatment period (33 days) indicate that there were no significant differences between all three groups in terms of reducing the risk of major venous thromboembolism and all-cause mortality. In addition the safety outcomes were similar between the Dabigatran etexilate and enoxaparin treatment groups.
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