Sixty patients with knee osteoarthritis scheduled for total knee arthroplasty and presenting with moderate-to-high pain catastrophizing scores were included in this study comparing a cognitive behavioural therapy-based education program to control. The primary outcome of interest was Visual Analog Scale (VAS) pain scores during activity at 12 months. Secondary outcomes of interest included VAS pain scores at rest, the Oxford Knee Score, Knee Injury and Osteoarthritis Outcomes Score, EQ-5D quality of life scores, Pain Self-Efficacy Questionnaire Scores, Pain Catastrophizing Scores, 6-minute walk test and sit-to-stand results. Follow-up occurred at 3 and 12 months post-operation. Results revealed no significant differences in all outcomes at all time-points, with exception of EQ-5D scores at 3 months post-operation which was significantly in favour of the standard care group.