Five studies with 190 patients with knee osteoarthritis (OA) were included in this meta-analysis comparing blood flow restriction (BFR) training under low load to high low strength training and low load strength training. The outcomes of interest included knee pain, knee function, knee muscle strength, and muscle volume. The results of the meta-analysis demonstrated no statistical significant differences between the BFR group and the low load group in pooled knee pain (p=0.63), and pooled knee function (p=0.95) outcomes. Additionally, pooled knee muscle strength (p=1.00) and pooled knee function (p=0.13) were not statistically significantly different between the BFR group and high load group. The pooling of muscle volume was not possible, as only one study reported the outcome for both comparisons.