No beneficial effects of oral vitamin D3 on cartilage volume or knee pain in knee OA .
This report has been verified
by one or more authors of the
original publication.
Effect of Vitamin D Supplementation on Tibial Cartilage Volume and Knee Pain Among Patients With Symptomatic Knee Osteoarthritis A Randomized Clinical Trial
JAMA. 2016 Mar 8;315(10):1005-13413 patients with knee osteoarthritis and low vitamin D levels were randomized to a monthly treatment of either oral vitamin D3 or an identical placebo for 24 months. The purpose of this study was to determine whether or not vitamin D supplements are beneficial in mitigating knee pain and improving knee cartilage volume, when compared with placebo up to 2 years. Findings indicated no significant difference in changes in tibial cartilage volume, WOMAC knee pain, tibiofemoral cartilage defects, or tibiofemoral bone marrow lesions between treatment groups.
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