Multiple PRP injections more effective than single injection at improving function, but not pain .
This study has been identified as potentially high impact.
OE's AI-driven High Impact metric estimates the influence a paper is likely to have by integrating signals from both the journal in which it is published and the scientific content of the article itself.
Developed using state-of-the-art natural language processing, the OE High Impact model more accurately predicts a study's future citation performance than journal impact factor alone.
This enables earlier recognition of clinically meaningful research and helps readers focus on articles most likely to shape future practice.
Comparison of the Clinical Effectiveness of Single Versus Multiple Injections of Platelet-Rich Plasma in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-analysis
Orthop J Sports Med.2019 Dec 16;7(12).Platelet-rich plasma (PRP) has gained prominence in recent years due to its potential regenerative and anti-inflammatory properties. Evidence on its efficacy has been mixed to date, though it has shown some promise in knee osteoarthritis. There is uncertainty in terms of the frequency and number of injections that provide optimal outcomes. In this study, the authors assessed randomized controlled trials comparing single to multiple PRP injections at 6-12 months in terms of pain and function improvements. Based on their meta-analysis, they found that multiple injections outperformed single injections in terms of function, but there was no difference in terms of pain.
Unlock the Full ACE Report
You have access to 4 more FREE articles this month.
Click below to unlock and view this ACE Reports
Unlock Now
Critical appraisals of the latest, high-impact randomized controlled trials and systematic reviews in orthopaedics
Access to OrthoEvidence podcast content, including collaborations with the Journal of Bone and Joint Surgery, interviews with internationally recognized surgeons, and roundtable discussions on orthopaedic news and topics
Subscription to The Pulse, a twice-weekly evidence-based newsletter designed to help you make better clinical decisions
Exclusive access to original content articles, including in-house systematic reviews, and articles on health research methods and hot orthopaedic topics
Or upgrade today and gain access to all OrthoEvidencecontent for as little as $1.99 per week.
Already have an account? Log in
0 of 4 monthly FREE articles unlocked
