Eight studies containing a total of 433 patients with chronic pain or chronic pain-related conditions were included in this meta-analysis comparing mindfulness cognitive-behavioural therapy (MBCT) to control (i.e., usual care; no treatment; psychoeducation). The pooled outcomes of interest included depression, pain intensity, mindfulness, pain interference, and pain acceptance. Comparisons were made between MBCT vs usual care, non-MBCT therapies, and active comparators, at both short term follow-up (post-intervention) and long term follow-up (up to 6 months post-treatment). Results revealed statistically significantly lower pooled depression scores in the MBCT group vs usual care at short term follow-up (p<0.05); however, no statistical significant differences were observed between MBCT and active comparators at short term or long term follow- up (p<0.05 for both). Pooled mindfulness scores were statistically significantly in favour of the MBCT group compared to the non-MBCT intervention subgroup at short term follow-up (p<0.05). Moreover, no statistical significant differences were observed in all other pooled outcome comparisons (p>0.05 for all).