Metal ions and moderate pseudotumor development reduced with large- vs. small-head MoM THA .
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A comparison of the effect of large and small metal-on-metal bearings in total hip arthroplasty on metal ion levels and the incidence of pseudotumour
Bone Joint J. 2018 Aug;100-B(8):1018-1024185 patients scheduled for metal-on-metal (MoM) total hip arthroplasty (THA) were randomized to either large-head or small-head articulation. Main outcomes of concern in this study included whole blood cobalt and chromium ion concentrations and the incidence of pseudotumor development on MRI over a 5-year follow-up. Cobalt levels were significantly lower in the large-head group compared to the small-head group at 36, 48, and 60 months postoperatively, while chromium levels were significantly lower in the large-head group compared to the small-head group at 12 and 48 months postoperatively. The incidence of moderate pseudotumor development was significantly lower in the large-head group compared to the small-head group.
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