Longer Lasting Clinical Improvements with PRP vs Corticosteroid Injections for Knee Osteoarthritis .
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Intra-articular platelet-rich plasma vs corticosteroids in the treatment of moderate knee osteoarthritis: a single-center prospective randomized controlled study with a 1-year follow up.
J Orthop Surg Res. 2020; 15: 257.Forty patients above the age of 55 with knee osteoarthritis (OA) were randomized to receive an intra-articular injection of platelet-rich plasma (PRP) or corticosteroid (triamcinolone acetonide) to improve pain and function. The primary outcome of interest was pain on a Visual Analog Scale (VAS) at 1 year post-treatment. Secondary outcomes of interest included the International Knee Documentation Committee (IKDC) score and the Knee Society Score (KSS). No significant differences were observed in all outcomes between the PRP and corticosteroid groups up to 5 weeks post-treatment. Yet at 15, 30, and 58 weeks post-treatment, all outcomes were significantly in favour of the PRP treatment arm compared to the corticosteroid treatment arm.
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