Liposomal Bupivacaine Does Not Decrease Postoperative Pain in Patients with Intracapsular Femoral Neck Fracture Treated with Hemiarthroplasty: HEAT-A Randomized, Controlled Trial.

研究概要

Fifty patients with isolated intracapsular femoral neck fractures undergoing hip hemiarthroplasty were randomized to receive either intraoperative liposomal bupivacaine with bupivacaine hydrochloride (n=25) or bupivacaine hydrochloride alone (n=25). The primary outcomes of interest were postoperative pain scores measured by the visual analog scale (VAS), total morphine milligram equivalents (MME) used, incidence of postoperative delirium, and time to ambulation with physical therapy. Secondary outcomes included hospital length of stay, discharge disposition, and complications. Outcomes were assessed up to discharge. Overall, the results showed no significant differences between groups in pain scores, total MME, or length of stay. The findings suggest that liposomal bupivacaine does not improve postoperative pain control, reduce opioid consumption, or enhance recovery outcomes in this patient population.