Leukocyte-poor platelet-rich plasma vs hyaluronic acid in treatment of symptomatic knee OA .
This report has been verified
by one or more authors of the
original publication.
This study has been identified as potentially high impact.
OE's AI-driven High Impact metric estimates the influence a paper is likely to have by integrating signals from both the journal in which it is published and the scientific content of the article itself.
Developed using state-of-the-art natural language processing, the OE High Impact model more accurately predicts a study's future citation performance than journal impact factor alone.
This enables earlier recognition of clinically meaningful research and helps readers focus on articles most likely to shape future practice.
Hyaluronic Acid Versus Platelet-Rich Plasma: A Prospective, Double-Blind Randomized Controlled Trial Comparing Clinical Outcomes and Effects on Intra-articular Biology for the Treatment of Knee Osteoarthritis
Am J Sports Med. 2017 Feb;45(2):339-346111 patients with Kellgren-Lawrence grade I-IV symptomatic knee osteoarthritis were randomized to three weekly intraarticular injections of either leukocyte-poor platelet-rich plasma (LP-PRP) or hyaluronic acid. Patients were assessed for pain and function over a 52-week follow-up. The primary outcome measure, the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) pain score, demonstrated no significant difference between groups at any time point. In contrast, pain scores on a visual analog scale (VAS) demonstrated significantly lower pain in the LP-PRP group compared to the HA group at 24- and 52-week follow-up. Similarly International Knee Documentation Committee (IKDC) subjective scores were significantly greater in the LP-PRP group compared to the HA group at 24 and 52 weeks.
Unlock the Full ACE Report
You have access to 4 more FREE articles this month.
Click below to unlock and view this ACE Reports
Unlock Now
Critical appraisals of the latest, high-impact randomized controlled trials and systematic reviews in orthopaedics
Access to OrthoEvidence podcast content, including collaborations with the Journal of Bone and Joint Surgery, interviews with internationally recognized surgeons, and roundtable discussions on orthopaedic news and topics
Subscription to The Pulse, a twice-weekly evidence-based newsletter designed to help you make better clinical decisions
Exclusive access to original content articles, including in-house systematic reviews, and articles on health research methods and hot orthopaedic topics
Or upgrade today and gain access to all OrthoEvidencecontent for as little as $1.99 per week.
Already have an account? Log in
0 of 4 monthly FREE articles unlocked
