Knee osteoarthritis: Plasma rich in growth factor (Endoret) vs. hyaluronic acid (Durolane) .
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Comparison of intra-articular injections of plasma rich in growth factors (PRGF-Endoret) versus Durolane hyaluronic acid in the treatment of patients with symptomatic osteoarthritis: a randomized controlled trial
Arthroscopy. 2013 Oct;29(10):1635-4396 patients with osteoarthritis of the knee (OA) were randomized to evaluate the efficacy of 3 injections of plasma rich in growth factors (PRGF-Endoret) against a single injection of Durolane hyaluronic acid (HA) in treating knee OA. Treatments were primarily evaluated based on the percentage of patients having a 30% decrease and a 50% decrease in the summed score for all the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) subscales, and the Lequesne score. The evidence presented in this study indicated that plasma rich in growth factors (PRGF-Endoret) is safe and a significantly superior treatment to Durolane hyaluronic acid (HA).
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