Effectiveness of aspiration in knee joint effusion management: a prospective randomized controlled study

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One hundred and sixty seven patients with acute knee joint effusion were randomized to either undergo knee aspiration or not, to determine whether this intervention is effective in improving clinical and functional outcomes. Results indicated that pain, edema, range of motion, analgesia intake, and knee function scores were significantly improved when knee effusion was treated with aspiration early on, however, this significant improvement was short lived due to the early re-accumulation of the effusion.