ISAKOS: Similiar Results with PRP and HA Injections for Early Knee Osteoarthritis .
PRP Injections Versus Viscosupplementation for Early Knee Osteoarthritis: A Randomized Double-Blind Trial
192 patients, older than 18 years, with chronic pain or swelling of knee and degeneration of the joint were randomized to be treated either with platelet rich plasma (PRP) or viscosupplementation (Hyaluronic Acid-HA) injections. To compare both treatment modalities for knee chondropathy or early osteoarthritis (OA), a year of clinical evaluation demonstrated that both groups had significant improvements in function and quality of life. No major adverse events were seen with both injections.
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