Intravenous Tranexamic Acid Does Not Improve Visual Field Clarity During Hip Arthroscopy .
Intravenous Tranexamic Acid Does Not Improve Visual Field Clarity During Hip Arthroscopy: A Double-Blind, Randomized, Placebo-Controlled Trial.
Arthroscopy . 2025 Aug;41(8):2865-2873.Seventy-eight patients with femoroacetabular impingement syndrome were randomized to receive 1,000 mg IV tranexamic acid (TXA) in 100 mL saline (n=39) or placebo saline (n=39). The primary outcome was arthroscopic visual field clarity (VFC), graded every 15 minutes on a 3-point scale. Secondary outcomes included the percentage of good VFC scores, composite VFC averages, and treatment-related adverse events. Outcomes were assessed intraoperatively only. Overall, the results of the study revealed no significant between-group differences in mean VFC scores (2.51 ± 0.41 vs 2.64 ± 0.42; P=.16) or percentage of good VFC ratings (56.4% vs 66.4%; P=.17). No adverse events occurred in either group. In conclusion, TXA did not improve visualization, suggesting it should not be routinely used for VFC enhancement in hip arthroscopy.
Unlock the Full ACE Report
You have access to 4 more FREE articles this month.
Click below to unlock and view this ACE Reports
Unlock Now
Critical appraisals of the latest, high-impact randomized controlled trials and systematic reviews in orthopaedics
Access to OrthoEvidence podcast content, including collaborations with the Journal of Bone and Joint Surgery, interviews with internationally recognized surgeons, and roundtable discussions on orthopaedic news and topics
Subscription to The Pulse, a twice-weekly evidence-based newsletter designed to help you make better clinical decisions
Exclusive access to original content articles, including in-house systematic reviews, and articles on health research methods and hot orthopaedic topics