Intraarticular ropivacaine infusion reduces pain intensity during mobilization after TKA .
This report has been verified
by one or more authors of the
original publication.
OrthoEvidence Journal (OE Journal) - ACE Report
OE Journal. 2013;1(11):135 Acta Orthop. 2011 Dec;82(6):692-8. Epub 2011 Oct 2536 patients with rheumatoid arthritis undergoing total knee arthroplasty were randomized to receive either intra-articular or extra-articular continuous infusion of local anaesthetics. Patients were assessed in terms of patient-controlled analgesia consumption and pain intensity during mobilization. The results demonstrate that patients receiving intra-articular infusion had decreased pain intensity during first exercises compared to the extra-articular infusion group. These findings indicate the potential for improving post-operative mobilization. However, there were no differences in pain relief at rest between the two treatment groups.
Was the allocation sequence adequately generated?
Was allocation adequately concealed?
Blinding Treatment Providers: Was knowledge of the allocated interventions adequately prevented?
Blinding Outcome Assessors: Was knowledge of the allocated interventions adequately prevented?
Blinding Patients: Was knowledge of the allocated interventions adequately prevented?
Was loss to follow-up (missing outcome data) infrequent?
Are reports of the study free of suggestion of selective outcome reporting?
Were outcomes objective, patient-important and assessed in a manner to limit bias (ie. duplicate assessors, Independent assessors)?
Was the sample size sufficiently large to assure a balance of prognosis and sufficiently large number of outcome events?
Was investigator expertise/experience with both treatment and control techniques likely the same (ie.were criteria for surgeon participation/expertise provided)?
Sim = 1
Incerto = 0,5
Não relevante = 0
Não = 0
A Avaliação dos Critérios de Relato avalia a transparência com que os autores relatam as caraterísticas metodológicas e do ensaio na publicação. A avaliação está dividida em cinco categorias que são apresentadas de seguida.
4/4
Randomization
3/4
Outcome Measurements
4/4
Inclusion / Exclusion
4/4
Therapy Description
5/5
Statistics
Detsky AS, Naylor CD, O'Rourke K, McGeer AJ, L'Abbé KA. J Clin Epidemiol. 1992;45:255-65
O Índice de Fragilidade é uma ferramenta que auxilia na interpretação de achados significativos, fornecendo uma medida de força para um resultado. O Índice de Fragilidade representa o número de eventos consecutivos que precisam de ser adicionados a um resultado dicotómico para que o resultado deixe de ser significativo. Um número pequeno representa um resultado mais fraco e um número grande representa um resultado mais forte.
Porque é que este estudo era necessário agora?
Approximately 66% of patients experience severe pain following total knee arthroplasty. Optimal pain relief must encompass an intervention that is delivered pre-operatively, peri-operatively, as well as post-operatively. Local infiltration and a single-shot injection or the continuous infusion of local anaesthetics is considered an effective alternative method to epidural analgesia and femoral block. Catheter insertion to facilitate continuous infusion of local anaesthetics, performed post-operatively, is an effective substitute for local infiltration. However, the optimal site of local anaesthetic administration is unknown, therefore, indicating the need for this study.
Qual era a principal questão de investigação?
What are the effects of either intra-articular or extra-articular continuous local anaesthetic infusion, on post-operative pain, in patients that have undergone total knee arthoplasty, measured at 48 hours?
- At 48 hours post-operatively, the overall patient-controlled analgesia consumption of morphine was similar between both treatment groups.
- There was no difference in the VAS score between groups during rest or with movement.
- There was greater physiotherapist satisfaction regarding the first mobilization in the patients receiving intra-articular infusion (p<0.05). At 48 hours post-operatively, patients receiving continuous intra-articular infusion with Ropivacaine had lower mean scores during exercise (p<0.07). Severe pain upon mobilization (VAS score greater than 7) occurred in 11 patients in the extra-articular group compared to 3 patients in the intra-articular group (p=0.03).
- No toxic side effects or post-operative complications, resulting from wound healing, were observed.
De que é que me devo lembrar mais?
Continuous intra-articular infusion with ropivacaine was effective in reducing pain intensity during first exercises. Therefore, early post-operative mobilization (within 24 hours post-op) could be improved following TKA. However, intra-articular infusion was not superior to extra-articular infusion with respect to pain relief at rest.
Como é que isto afectará o tratamento dos meus doentes?
Future studies with larger sample sizes are required to provide a more accurate comparison of outcomes between groups and to additionally compare complications rates.
AVISO LEGAL
O conteúdo desta página destina-se apenas a fins informativos e não pretende substituir o aconselhamento, diagnóstico ou tratamento médico profissional. Se necessitar de tratamento médico, procure sempre o conselho do seu médico ou dirija-se ao serviço de urgência mais próximo. As opiniões, crenças e pontos de vista expressos pelos indivíduos no conteúdo encontrado nesta página não reflectem as opiniões, crenças e pontos de vista da OrthoEvidence.
0 de 4 artigos mensais GRATUITOS desbloqueados
