.gif)
Intra-articular sodium hyaluronate vs placebo over 6 month follow-up in knee OA treatment .
This study has been identified as potentially high impact.
OE's AI-driven High Impact metric estimates the influence a paper is likely to have by integrating signals from both the journal in which it is published and the scientific content of the article itself.
Developed using state-of-the-art natural language processing, the OE High Impact model more accurately predicts a study's future citation performance than journal impact factor alone.
This enables earlier recognition of clinically meaningful research and helps readers focus on articles most likely to shape future practice.
Hyaluronic acid in the treatment of osteoarthritis of the knee
Rheumatology (Oxford). 1999 Jul;38(7):602-7.100 patients with persistent mild to moderate osteoarthritis of the knee were randomized to receive intra-articular injections of either sodium hyaluronate (Hyalgan) or saline placebo. The purpose of this study was to compare pain and function, primarily, as well as patient global assessment, patient satisfaction and development of adverse effects between groups. Results of the primary end points demonstrated significant lower pain in the HA group over 6 month, and better functional outcome over 2 month follow-up, but not 6 month follow-up. Incidence of adverse events was similar between groups, though two sever adverse events in the HA group were considered related to treatment, while no adverse events in the placebo group were deemed related to treatment.
Unlock the Full ACE Report
You have access to 4 more FREE articles this month.
Click below to unlock and view this ACE Reports
Unlock Now
Critical appraisals of the latest, high-impact randomized controlled trials and systematic reviews in orthopaedics
Access to OrthoEvidence podcast content, including collaborations with the Journal of Bone and Joint Surgery, interviews with internationally recognized surgeons, and roundtable discussions on orthopaedic news and topics
Subscription to The Pulse, a twice-weekly evidence-based newsletter designed to help you make better clinical decisions
Exclusive access to original content articles, including in-house systematic reviews, and articles on health research methods and hot orthopaedic topics
Or upgrade today and gain access to all OrthoEvidencecontent for as little as $1.99 per week.
Already have an account? Log in
0 of 4 monthly FREE articles unlocked
