Thirty healthy patients were included in this randomized trial comparing 8 weeks of virtual reality (VR) video game based therapy and control with regards to the improvement of non-dominant hand function and grip strength. Outcomes of interest included the Jebsen Taylor Hand Function Test (JTHFT) sub-scores and total score, as well as hand grip strength, tip grip strength, key grip strength and triple grip strength. Outcomes were assessed at baseline and when following the completion of the 8 week intervention. Statistically significantly favourable JTHFT total scores (p=0.003), writing scores (p=0.012), moving light objects scores (p=0.001), and moving heavy objects scores (p<0.001) were observed in the VR video game group compared to the control group. Hand grip strength (p=0.001), tip grip strength (p<0.001), and triple grip strength (p<0.001) were statistically significantly in favour of the VR video game group.