High and standard concentrations of intranasal fentanyl reduce pain in children in the ED .
This report has been verified
by one or more authors of the
original publication.
Equivalency of two concentrations of fentanyl administered by the intranasal route for acute analgesia in children in a paediatric emergency department: a randomized controlled trial
Emerg Med Australas. 2011 Apr;23(2):202-8. doi: 10.1111/j.1742-6723.2011.01391.x. Epub 2011 Feb 8199 children with deformed closed long bone fractures were randomized to either receive a standard concentration of intranasal fentanyl (SINF) or a high concentration of INF (HINF) to determine if there were any differences in efficacy of the two concentrations. Following assessments in the paediatric emergency department (ED) over a 30 minute period, the results displayed that both the SINF (50 ug/mL) and HINF (300 ug/mL) concentrations provided children with deformed closed long bone fractures in the ED with similar improvements in pain.
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