Hemodynamic Changes In The Prone Position According to Fluid Loading After Anaesthesia Induction .
Hemodynamic changes in the prone position according to fluid loading after anaesthesia induction in patients undergoing lumbar spine surgery: a randomized, assessor-blind, prospective study.
Ann Med. 2024 Dec;56(1):2356645.Eighty patients undergoing elective lumbar spine surgery were randomized to receive either fluid maintenance (n=40) or fluid loading (n=40). Both groups received intravenous fluids at 2 ml/kg/h until surgical incision, while the fluid loading group received an additional 5 ml/kg over 10 minutes after anesthesia induction. The primary outcome was the incidence of hypotension before surgical incision. Secondary outcomes included changes in mean blood pressure (mBP), heart rate (HR), pleth variability index (PVi), stroke volume variation (sVV), pulse pressure variation (PPV), stroke volume index (SVI), cardiac index (CI), and postoperative complications up to postoperative day 2. Outcomes were assessed at multiple time points until surgical incision. Overall, fluid loading significantly reduced the incidence of hypotension (p=0.014) and was particularly effective in patients with a baseline PVi >16. Other hemodynamic parameters, such as PVi, sVV, and PPV, were significantly improved immediately after fluid loading. However, no significant differences were found in postoperative complications or hospital length of stay between the two groups. The findings suggest that intravenous fluid loading is beneficial in preventing hypotension in patients positioned prone for surgery, particularly for those with a high baseline PVi.
Unlock the Full ACE Report
You have access to 4 more FREE articles this month.
Click below to unlock and view this ACE Reports
Unlock Now
Critical appraisals of the latest, high-impact randomized controlled trials and systematic reviews in orthopaedics
Access to OrthoEvidence podcast content, including collaborations with the Journal of Bone and Joint Surgery, interviews with internationally recognized surgeons, and roundtable discussions on orthopaedic news and topics
Subscription to The Pulse, a twice-weekly evidence-based newsletter designed to help you make better clinical decisions
Exclusive access to original content articles, including in-house systematic reviews, and articles on health research methods and hot orthopaedic topics