Intra-articular steroids in osteoarthritis

12 patients with bilateral knee osteoarthritis had one knee randomized to injection with 20mg triamcinolone hexacetonide, and the other knee randomized to injection with saline. The purpose of this study was to compare pain, knee stiffness & tenderness, patient preference, and thermographic indices between knees over a 6-week follow-up. While reporting of between-group comparisons was not very extensive, there was a report of significantly higher patient preference for knees treated with a 20mg triamcinolone hexacetonide injection compared to saline injection.