18 patients undergoing total knee arthroplasty were randomized to receive either graded motor with a traditional rehabilitation program (GMI; n=9) or traditional rehabilitation (control; n=9). The primary outcomes of interest were pain intensity during activity and rest and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) scores after 6 weeks. Secondary outcomes of interest were range of motion (ROM), muscle strength, Timed Up and Go test (TUG), mental chronometer, Movement Imagery Questionnaire-3 (MIQ-3), lateralization performance, Central Sensitization Inventory (CSI), Pain Catastrophizing Scale (PCS), and Tampa Kinesiophobia Scale (TKS) after 6 weeks. MIQ-3, lateralization knee recognition accuracy, PCS, TKS, VAS pain during activity, and rest were all significantly better in the GMI group at 6 weeks compared to the control.