Gabapentin provides no added benefit to multimodal analgesia for total knee arthroplasty .
This report has been verified
by one or more authors of the
original publication.
Gabapentin does not improve multimodal analgesia outcomes for total knee arthroplasty: a randomized controlled trial
Can J Anaesth. 2013 May;60(5):423-31. doi: 10.1007/s12630-013-9902-1. Epub 2013 Mar 12.Exclusive Author Interview
Dr. J. E. Paul discusses how Gabapentin provides no added benefit to multimodal analgesia for total knee arthroplasty
101 total knee arthroplasty patients were randomized to evaluate gabapentin’s efficacy in reducing pain and morphine consumption. They were allocated to receive gabapentin 600 mg preoperatively followed by 200 mg every eight hours for two days or to the same regimen of placebo treatment. Evaluation after the 72-hour study period demonstrated no differences between the two treatment groups in postoperative morphine consumption, pain scores, patient satisfaction, or length of hospital stay.
Unlock the Full ACE Report
You have access to 4 more FREE articles this month.
Click below to unlock and view this ACE Reports
Unlock Now
Critical appraisals of the latest, high-impact randomized controlled trials and systematic reviews in orthopaedics
Access to OrthoEvidence podcast content, including collaborations with the Journal of Bone and Joint Surgery, interviews with internationally recognized surgeons, and roundtable discussions on orthopaedic news and topics
Subscription to The Pulse, a twice-weekly evidence-based newsletter designed to help you make better clinical decisions
Exclusive access to original content articles, including in-house systematic reviews, and articles on health research methods and hot orthopaedic topics
Or upgrade today and gain access to all OrthoEvidencecontent for as little as $1.99 per week.
Already have an account? Log in
0 of 4 monthly FREE articles unlocked
